BMP1 抗体 (AA 957-986)
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Quick Overview for BMP1 抗体 (AA 957-986) (ABIN3030175)
抗原
See all BMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 957-986
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纯化方法
- Purified
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免疫原
- A portion of amino acids 957-986 from the human protein was used as the immunogen for this BMP1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BMP1 (Bone Morphogenetic Protein 1 (BMP1))
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别名
- BMP1
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背景
- The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
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UniProt
- P13497
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途径
- Lipid Metabolism
抗原
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