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BCL6 抗体 (AA 676-704)

This anti-BCL6 antibody is a 小鼠 单克隆 antibody detecting BCL6 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3030107
发货至: 中国

Quick Overview for BCL6 抗体 (AA 676-704) (ABIN3030107)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

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宿主

  • 92
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  • 1
小鼠

克隆类型

  • 94
  • 62
单克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

305CT16-3-3
  • 抗原表位

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    AA 676-704

    纯化方法

    Purified

    免疫原

    A portion of amino acids 676-704 from the human protein was used as the immunogen for this BCL-6 antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Titration of the BCL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the BCL-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    BCL-6

    背景

    The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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