BCL6 抗体 (AA 676-704)
Our Local Distributor
北京 101111
Quick Overview for BCL6 抗体 (AA 676-704) (ABIN3030107)
抗原
See all BCL6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 676-704
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 676-704 from the human protein was used as the immunogen for this BCL-6 antibody.
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- Titration of the BCL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the BCL-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
-
别名
- BCL-6
-
背景
- The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
-
UniProt
- P41182
-
途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
-