Aurora Kinase C 抗体 (AA 3-38)
Quick Overview for Aurora Kinase C 抗体 (AA 3-38) (ABIN3030078)
抗原
See all Aurora Kinase C (AURKC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-38
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 3-38 from the human protein was used as the immunogen for this Aurora-C antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Aurora-C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Aurora-C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Aurora Kinase C (AURKC)
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别名
- Aurora-C
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背景
- Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
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UniProt
- Q9UQB9
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途径
- Cell Division Cycle, Maintenance of Protein Location
抗原
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