Aurora A 抗体 (AA 93-120)
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Quick Overview for Aurora A 抗体 (AA 93-120) (ABIN3030070)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 93-120
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Aurka antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Aurka antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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别名
- Aurka
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背景
- Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.
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UniProt
- P97477
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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