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APOE 抗体 (AA 263-292)

Name: APOE 抗体 (AA 263-292)
SKU: ABIN3029997
Availability: OutOfStock

APOE 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of lysate from human plasma tissue lysate using ApoE antibody diluted at 1:1000. (APOE 抗体 (AA 263-292))

IHC analysis of FFPE human hepatocarcinoma tissue stained with ApoE antibody (APOE 抗体 (AA 263-292))

IHC

3 images

产品编号 ABIN3029997

发货至: 中国

Datasheet as PDF

抗原 See all APOE 抗体

APOE (Apolipoprotein E (APOE))
抗原表位
15

15

15

5

5

5

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 263-292
适用
101

75

56

2

2

2

1

1
人
宿主
102

22

13

2
兔
Compatible Secondaries
克隆类型
104

34
多克隆
标记
59

18

12

7

4

4

4

4

4

4

3

3

3

3

3

2

2
This APOE antibody is un-conjugated
应用范围
110

56

39

39

29

25

20

12

10

9

7

5

3

2

2

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

交叉反应（详细）

Expected species reactivity: Primate, Rabbit

纯化方法

Antigen affinity purified

免疫原

A portion of amino acids 263-292 from the human protein was used as the immunogen for this ApoE antibody.

亚型

Ig Fraction

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APOE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the ApoE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

APOE (Apolipoprotein E (APOE))

别名

ApoE (Apolipoprotein E) (APOE 产品)

别名

ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody

背景

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

UniProt

P02649

途径

Regulation of Cell Size, Lipid Metabolism