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APOE 抗体 (AA 263-292)

This anti-APOE antibody is a 兔 多克隆 antibody detecting APOE in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN3029997
发货至: 中国

Quick Overview for APOE 抗体 (AA 263-292) (ABIN3029997)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

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宿主

  • 123
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克隆类型

  • 121
  • 59
多克隆

标记

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This APOE antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 263-292

    交叉反应 (详细)

    Expected species reactivity: Primate, Rabbit

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 263-292 from the human protein was used as the immunogen for this ApoE antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ApoE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    ApoE (Apolipoprotein E)

    背景

    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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