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CD13 抗体 (AA 156-184)

This anti-CD13 antibody is a 小鼠 单克隆 antibody detecting CD13 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3029889
发货至: 中国

Quick Overview for CD13 抗体 (AA 156-184) (ABIN3029889)

抗原

See all CD13 (ANPEP) 抗体
CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

适用

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宿主

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小鼠

克隆类型

  • 128
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单克隆

标记

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This CD13 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

505CT12-1-2
  • 抗原表位

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    AA 156-184

    纯化方法

    Purified

    免疫原

    A portion of amino acids 156-184 from the human protein was used as the immunogen for this ANPEP antibody.

    亚型

    IgG2a
  • 应用备注

    Titration of the ANPEP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ANPEP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

    别名

    ANPEP

    背景

    Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

    UniProt

    P15144

    途径

    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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