ANGPTL4 抗体 (AA 138-167)
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Quick Overview for ANGPTL4 抗体 (AA 138-167) (ABIN3029955)
抗原
See all ANGPTL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 138-167
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纯化方法
- Purified
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免疫原
- A portion of amino acids 138-167 from the human protein was used as the immunogen for this ANGPTL4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ANGPTL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ANGPTL4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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别名
- ANGPTL4
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背景
- ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.
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UniProt
- Q9BY76
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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