BMPR1A 抗体 (AA 30-60)
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Quick Overview for BMPR1A 抗体 (AA 30-60) (ABIN3030186)
抗原
See all BMPR1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-60
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 30-60 from the human protein was used as the immunogen for this ALK3 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ALK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ALK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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别名
- ALK3
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背景
- The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A/ALK3 and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
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UniProt
- P36894
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途径
- Stem Cell Maintenance
抗原
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