AIM2 抗体 (AA 1-50)
Quick Overview for AIM2 抗体 (AA 1-50) (ABIN3029828)
抗原
See all AIM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1-50 from the human protein was used as the immunogen for this AIM2 antibody.
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亚型
- Ig Fraction
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anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibody
AIM2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3C4G11 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibodyAIM2 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7G12D1 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 81-326) antibodyAIM2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (Internal Region) antibodyAIM2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibodyAIM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 14-215) antibodyAIM2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 255-354) antibodyAIM2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the AIM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the AIM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- AIM2 (Absent in Melanoma 2 (AIM2))
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别名
- AIM2
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背景
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. [UniProt]
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UniProt
- O14862
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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