alpha Fetoprotein 抗体 (AA 300-329)
Quick Overview for alpha Fetoprotein 抗体 (AA 300-329) (ABIN3029916)
抗原
See all alpha Fetoprotein (AFP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-329
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 300-329 from the human protein was used as the immunogen for this AFP antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the AFP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the AFP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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别名
- AFP
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背景
- Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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UniProt
- P02771
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途径
- C21-Steroid Hormone Metabolic Process
抗原
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