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SIRT6 抗体

This 小鼠 单克隆 antibody specifically detects SIRT6 in WB, IP, ICC 和 IF. It exhibits reactivity toward 人, 小鼠, 大鼠 和 灵长类.
产品编号 ABIN4953432
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIRT6 抗体 (ABIN4953432)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

适用

  • 88
  • 31
  • 17
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 灵长类

宿主

  • 86
  • 11
  • 2
小鼠

克隆类型

  • 80
  • 19
单克隆

标记

  • 56
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT6 antibody is un-conjugated

应用范围

  • 78
  • 35
  • 31
  • 14
  • 14
  • 11
  • 10
  • 7
  • 6
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

6C9-D10-D3
  • 纯化方法

    Protein G affinity

    免疫原

    A human recombinant protein was used as the immunogen for this SIRT6 antibody.

    亚型

    IgG1
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable

    限制

    仅限研究用
  • 缓冲液

    Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

    储存条件

    -20 °C

    储存方法

    Store the SIRT6 antibody at -20°C.
  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    SIRT6

    背景

    NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]

    UniProt

    Q8N6T7
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