SIRT6 抗体
Our Local Distributor
北京 101111
Quick Overview for SIRT6 抗体 (ABIN4953432)
抗原
See all SIRT6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Protein G affinity
-
免疫原
- A human recombinant protein was used as the immunogen for this SIRT6 antibody.
-
亚型
- IgG1
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable
-
限制
- 仅限研究用
-
-
-
缓冲液
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
-
储存条件
- -20 °C
-
储存方法
- Store the SIRT6 antibody at -20°C.
-
-
- SIRT6 (Sirtuin 6 (SIRT6))
-
别名
- SIRT6
-
背景
- NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]
-
UniProt
- Q8N6T7
抗原
-