EIF4E 抗体
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北京 101111
Quick Overview for EIF4E 抗体 (ABIN4953242)
抗原
See all EIF4E 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity
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免疫原
- A human recombinant protein was used as the immunogen for this EIF4E antibody.
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亚型
- IgG1
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应用备注
- The stated application concentrations are suggested starting points. Titration of the EIF4E antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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缓冲液
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
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储存条件
- -20 °C
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储存方法
- Store the EIF4E antibody at -20°C.
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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别名
- EIF4E
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背景
- Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [UniProt]
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UniProt
- P06730
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途径
- BCR Signaling
抗原
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