EIF4E
适用: 人
IHC, ELISA, IF
宿主: 兔
Polyclonal
unconjugated
应用备注
The stated application concentrations are suggested starting points. Titration of the EIF4E antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
缓冲液
Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
储存条件
-20 °C
储存方法
Store the EIF4E antibody at -20°C.
抗原
EIF4E
(Eukaryotic Translation Initiation Factor 4E (EIF4E))
别名
EIF4E
背景
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [UniProt]