PDGFRB 抗体 (AA 40-72)
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Quick Overview for PDGFRB 抗体 (AA 40-72) (ABIN3029811)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-72
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纯化方法
- Purified
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免疫原
- A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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别名
- PDGFR beta (CD140b)
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背景
- PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
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UniProt
- P09619
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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