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- 抗原 See all KEAP1 抗体
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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抗原表位
- AA 422-449
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KEAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应 （详细）
- Expected species reactivity: Pig
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KEAP1 Primary Antibody
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anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KEAP1 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人, 小鼠 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1F10B6 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7G4B10 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibodyKEAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (C-Term) antibodyKEAP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 65-160) antibodyKEAP1 适用: 人, 小鼠, 大鼠, Pig, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibodyKEAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibodyVerified KEAP1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-624) antibodyKEAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 327-624) antibodyKEAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at 4°C for up to one month. For long term, aliquot the KEAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- 别名
- KEAP1 (KEAP1 产品)
- 别名
- INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
- 背景
- KEAP1 acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome [UniProt]
- UniProt
- Q14145
- 途径
- Maintenance of Protein Location
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