RBBP4 / RbAp48 / NURF55 抗体
The 兔 多克隆 anti-RBBP4 / RbAp48 / NURF55 antibody is suitable to detect RBBP4 / RbAp48 / NURF55 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC (p), WB 和 IHC (fro).
产品编号 ABIN4952377
发货至:
中国
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Quick Overview for RBBP4 / RbAp48 / NURF55 抗体 (ABIN4952377)
抗原
RBBP4 / RbAp48 / NURF55
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
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纯化方法
- Antigen affinity
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免疫原
- Amino acids EDNIMQVWQMAENIYNDEDPEGSVDPEGQGS of human Retinoblastoma binding protein 4 were used as the immunogen for the RBBP4 antibody.
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亚型
- IgG
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anti-RBBP4 / RbAp48 / NURF55 antibody
适用: 人 IHC (p), WB 宿主: 小鼠 Monoclonal 9F3 unconjugated
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应用备注
- Optimal dilution of the RBBP4 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the RBBP4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- RBBP4 / RbAp48 / NURF55
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背景
- Retinoblastoma binding protein 4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene. This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. And it is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q09028
抗原
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