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PRNP 抗体 (AA 143-230)

PRNP 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4952280
发货至: 中国
  • 抗原 See all PRNP 抗体
    PRNP (Prion Protein (PRNP))
    抗原表位
    • 15
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 143-230
    适用
    • 89
    • 34
    • 30
    • 12
    • 11
    • 3
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 87
    • 18
    • 3
    • 2
    • 1
    克隆类型
    • 78
    • 33
    多克隆
    标记
    • 52
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This PRNP antibody is un-conjugated
    应用范围
    • 57
    • 36
    • 27
    • 26
    • 16
    • 16
    • 10
    • 7
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 143-230 of human PRNP were used as the immunogen for the PrP antibody.
    亚型
    IgG
    Top Product
    Discover our top product PRNP Primary Antibody
  • 应用备注
    Optimal dilution of the PrP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PrP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PRNP (Prion Protein (PRNP))
    别名
    Prion protein Antibody (PrP) (PRNP 产品)
    背景
    PRNP (prion protein), also known as CD230 or PrP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. (1991) identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6 % similarity in amino acid sequences.
    UniProt
    P04156
    途径
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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