POR 抗体
Quick Overview for POR 抗体 (ABIN4952222)
抗原
See all POR 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity
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免疫原
- Amino acids RNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTK of human Cytochrome P450 Oxidoreductase were used as the immunogen for the POR antibody.
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亚型
- IgG
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anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 77-518) antibody
POR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-250) antibodyPOR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (N-Term) antibodyKO Validated POR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 2-671) antibodyPOR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyKO Validated POR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 633-668), (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 131-180) antibodyPOR 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼, Pig, Bat, 猴, Hamster, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the POR antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the POR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- POR (P450 (Cytochrome) Oxidoreductase (POR))
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别名
- POR / CYPOR / Cytochrome P450 Oxidoreductase
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背景
- POR is a membrane-bound enzyme required for electron transfer from NADPH to Cytochrome p450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal p450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined p450C17 and p450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
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UniProt
- P16435
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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