PKC eta 抗体 (AA 30-389)
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Quick Overview for PKC eta 抗体 (AA 30-389) (ABIN4952175)
抗原
See all PKC eta (PRKCH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-389
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 30-389 of human PKC eta were used as the immunogen for the PKC eta antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PKC eta antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the PKC eta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
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别名
- PKC eta
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背景
- PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
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UniProt
- P24723
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途径
- Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
抗原
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