BIK 抗体 (AA 1-123)
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Quick Overview for BIK 抗体 (AA 1-123) (ABIN4950330)
抗原
See all BIK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-123
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 1-123 of human BIK were used as the immunogen for the BIK antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BIK antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the BIK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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别名
- BIK / BCL2-interacting killer
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背景
- Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
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UniProt
- Q13323
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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