BCL10 抗体 (AA 1-233)
Our Local Distributor
北京 101111
Quick Overview for BCL10 抗体 (AA 1-233) (ABIN4950310)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-233
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids 1-233 of human Bcl10 were used as the immunogen for the Bcl10 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Bcl10 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the Bcl10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
-
别名
- Bcl10
-
背景
- BCL10, B-cell CLL/lymphoma 10, gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The BCL10 gene is mapped to chromosome 1p22. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. And this protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
-
UniProt
- O95999
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
-