FOXA1 抗体
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北京 101111
Quick Overview for FOXA1 抗体 (ABIN4949697)
抗原
See all FOXA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- A human recombinant partial protein corresponding to amin acids 372-472 was used as the immunogen for this FOXA1 antibody.
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亚型
- IgG2b kappa
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anti-Forkhead Box A1 (FOXA1) (C-Term) antibody
Verified FOXA1 适用: 人, 小鼠 WB, IF, FACS, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人 WB, IHC, IF, FACS, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1512 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 WB, IHC, StM 宿主: 小鼠 Monoclonal FOXA1-1518 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 372-472) antibodyFOXA1 适用: 人, 大鼠 IHC, ISt, StM 宿主: 小鼠 Monoclonal FOXA1-1241 unconjugated
anti-Forkhead Box A1 (FOXA1) (C-Term) antibodyFOXA1 适用: 人 WB, IF, IHC (p), ICC, IP, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 263-472) antibodyFOXA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Forkhead Box A1 (FOXA1) (AA 367-472) antibodyFOXA1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FOXA1 antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/10^6 cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the FOXA1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- FOXA1 (Forkhead Box A1 (FOXA1))
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别名
- FOXA1
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背景
- The transcription factor Forkhead-box A1, also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. Its expression correlates with estrogen receptor (ER)-positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
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基因ID
- 3169
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
抗原
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