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Filaggrin 抗体 (AA 998-1104)

FLG 适用: 人 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal FLG-1561 unconjugated
产品编号 ABIN4949675
发货至: 中国
  • 抗原 See all Filaggrin (FLG) 抗体
    Filaggrin (FLG)
    抗原表位
    • 15
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 998-1104
    适用
    • 65
    • 17
    • 11
    宿主
    • 48
    • 24
    小鼠
    克隆类型
    • 43
    • 29
    单克隆
    标记
    • 43
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Filaggrin antibody is un-conjugated
    应用范围
    • 38
    • 33
    • 24
    • 24
    • 14
    • 13
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
    克隆位点
    FLG-1561
    亚型
    IgG
    Top Product
    Discover our top product FLG Primary Antibody
  • 应用备注
    Optimal dilution of the Filaggrin antibody should be determined by the researcher.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    Store the Filaggrin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Filaggrin (FLG)
    别名
    Filaggrin (FLG 产品)
    背景
    Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
    途径
    Sensory Perception of Sound, Stem Cell Maintenance
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