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EpCAM 抗体 (Extracellular)

The 小鼠 单克隆 anti-EpCAM antibody is suitable to detect EpCAM in samples from 人, Cat, 犬 和 豚鼠. It has been validated for WB, IF, ELISA 和 IHC (p).
产品编号 ABIN4949641
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EpCAM 抗体 (Extracellular) (ABIN4949641)

抗原

See all EpCAM (EPCAM) 抗体
EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

适用

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人, Cat, 犬, 豚鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This EpCAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

EGP40-1384
  • 抗原表位

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    AA 100-224, Extracellular

    原理

    EpCAM Antibody / Extracellular domain (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A human partial recombinant protein corresponding to amino acids 100-224 (extracellular domain) was used as the immunogen for the EpCAM antibody.

    亚型

    IgG
  • 应用备注

    Titering of the EpCAM antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the EpCAM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

    别名

    EpCAM

    背景

    EpCAM (Epithelial Cell Adhesion Molecule), also known as CD326, plays a crucial role in various cellular processes and has been linked to the development and progression of cancer. EpCAM is a transmembrane glycoprotein that is expressed in high levels on the surface of epithelial cells. In cancer cells, the expression of EpCAM is often upregulated, leading to increased cell proliferation, invasion, and metastasis. Studies have shown that high levels of EpCAM are associated with poor prognosis in various types of cancer, including breast, colon, and lung cancer. The overexpression of EpCAM in cancer cells makes it an attractive target for diagnostic and therapeutic purposes. Researchers are exploring the use of EpCAM as a biomarker for early cancer detection through blood tests and imaging techniques. In addition, EpCAM-targeted therapies, such as monoclonal antibodies and immunotherapies, are being developed to specifically target and kill cancer cells that overexpress EpCAM.

    UniProt

    P16422
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