Desmoglein 1 抗体 (Internal Region)
Quick Overview for Desmoglein 1 抗体 (Internal Region) (ABIN4949605)
抗原
See all Desmoglein 1 (DSG1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Internal Region
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the DSG1 antibody.
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亚型
- IgG1 kappa
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anti-Desmoglein 1 (DSG1) (AA 30-90) antibody
DSG1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal 32-2B unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-544M unconjugated
anti-Desmoglein 1 (DSG1) (AA 384-539) antibodyDSG1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 1-1049) antibodyDSG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (N-Term) antibodyDSG1 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 800-1049) antibodyDSG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) (AA 710-961) antibodyDSG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 1 (DSG1) antibodyDSG1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the DSG1 antibody should be determined by the researcher.\. FACS: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL,Immunoprecipitation: suitable
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the DSG1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Desmoglein 1 (DSG1)
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别名
- Desmoglein 1 / DSG1
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背景
- Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
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途径
- Cell-Cell Junction Organization
抗原
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