CD81 抗体 (full length)
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北京 101111
Quick Overview for CD81 抗体 (full length) (ABIN4949542)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- CD81 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full length human protein was used as the immunogen for the CD81 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the CD81 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD81 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD81
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别名
- CD81
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背景
- This mAb recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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