CD79a 抗体 (AA 202-216)
Quick Overview for CD79a 抗体 (AA 202-216) (ABIN4949534)
抗原
See all CD79a (CD79A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 202-216
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the CD79a antibody.
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亚型
- IgG1 kappa
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anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 30-193) antibody
CD79A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 兔 Monoclonal IGA-1790R unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 小鼠 Monoclonal JCB117-HM47-A9 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-145) antibodyCD79A 适用: 人 IF, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibodyCD79A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibodyCD79A 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal rIGA-764 unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody (FITC)CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, Opossum ICFC 宿主: 小鼠 Monoclonal HM57 FITC
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, 犬, Non-Human Primate FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal HM47 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, Opossum FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HM57 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibody (PE)CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, 犬, Non-Human Primate ICFC 宿主: 小鼠 Monoclonal HM47 PE
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应用备注
- Optimal dilution of the CD79a antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD79a antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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别名
- CD79a
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背景
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CD79a, also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR). This occurs in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface.
CD79a plays multiple and diverse roles in B cell development and function. The CD79a/b heterodimer associates non-covalently with the immunoglobulin heavy chain through its transmembrane region, thus forming the BCR along with the immunoglobulin light chain and the pre-BCR when associated with the surrogate light chain in developing B cells. Association of the CD79a/b heterodimer with the immunoglobulin heavy chain is required for surface expression of the BCR and BCR induced calcium flux and protein tyrosine phosphorylation. Genetic deletion of the transmembrane exon of CD79A results in loss of CD79a protein and a complete block of B cell development at the pro to pre B cell transition. Similarly, humans with homozygous splice variants in CD79A predicted to result in loss of the transmembrane region and a truncated or absent protein display agammaglobulinemia and no peripheral B cells. [Wiki]
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途径
- BCR Signaling
抗原
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