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SELPLG 抗体

The 小鼠 单克隆 anti-SELPLG antibody (Clone PSGL1-1601) (ABIN4949414) specifically detects SELPLG in FACS, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN4949414
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SELPLG 抗体 (ABIN4949414)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SELPLG antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PSGL1-1601
  • 纯化方法

    Protein G affinity

    免疫原

    Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the PSGL-1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the PSGL-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    CD162 / P selectin glycoprotein ligand 1 / PSGL-1

    背景

    P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
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