SELPLG 抗体
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北京 101111
Quick Overview for SELPLG 抗体 (ABIN4949414)
抗原
See all SELPLG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity
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免疫原
- Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the PSGL-1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the PSGL-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- SELPLG (Selectin P Ligand (SELPLG))
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别名
- CD162 / P selectin glycoprotein ligand 1 / PSGL-1
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背景
- P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
抗原
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