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PTH 抗体 (N-Term)

This anti-PTH antibody is a 兔 多克隆 antibody detecting PTH in IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN4949381
发货至: 中国

Quick Overview for PTH 抗体 (N-Term) (ABIN4949381)

抗原

See all PTH 抗体
PTH (Parathyroid Hormone (PTH))

适用

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宿主

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克隆类型

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多克隆

标记

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This PTH antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    纯化方法

    Protein A affinity chromatography

    免疫原

    A synthetic peptide from the N-terminal region of human Parathyroid hormone was used as the immunogen for the PTH antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PTH antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the PTH antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    PTH (Parathyroid Hormone (PTH))

    别名

    Parathyroid Hormone

    物质类

    Hormone

    背景

    PTH/Parathyroid hormone is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

    途径

    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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