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Recombinant CD45RB 抗体

This anti-CD45RB antibody is a 兔 单克隆 antibody detecting CD45RB in IHC (p). Suitable for 人.
产品编号 ABIN4949302
发货至: 中国

Quick Overview for Recombinant CD45RB 抗体 (ABIN4949302)

抗原

See all CD45RB 抗体
CD45RB

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 101
  • 10
  • 1
单克隆

标记

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This CD45RB antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PTPRC-1783R
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    Human B lymphocytes were used as immunogen for this recombinant CD45RB antibody.

    亚型

    IgG kappa
  • 应用备注

    Due to variation in protocol and secondary antibody used, the recombinant CD45RB antibody may need to be titered for optimal performance.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistology (FFPE): 0.5-1 μg/mL for 30 minutes at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    The recombinant CD45RB antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD45RB

    别名

    CD45RB

    背景

    CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage.
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