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Recombinant Cadherin-16 抗体

This anti-Cadherin-16 antibody is a 兔 单克隆 antibody detecting Cadherin-16 in IF, FACS 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4949256
发货至: 中国

Quick Overview for Recombinant Cadherin-16 抗体 (ABIN4949256)

抗原

See all Cadherin-16 (CDH16) 抗体
Cadherin-16 (CDH16)

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This Cadherin-16 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CDH16-1532R
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    Human protein was used as the immunogen for the recombinant Cadherin 16 antibody.

    亚型

    IgG kappa
  • 应用备注

    Optimal dilution of the recombinant Cadherin 16 antibody to be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/10e6 cells,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    Cadherin-16 (CDH16)

    别名

    Cadherin 16

    背景

    Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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