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Recombinant Cadherin-16 抗体

CDH16 适用: 人, 小鼠, 大鼠 IF, FACS, IHC (p) 宿主: 兔 Monoclonal CDH16-1532R unconjugated Recombinant Antibody
产品编号 ABIN4949254
发货至: 中国
  • 抗原 See all Cadherin-16 (CDH16) 抗体
    Cadherin-16 (CDH16)
    抗体类型
    Recombinant Antibody
    适用
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    人, 小鼠, 大鼠
    宿主
    • 54
    • 34
    • 1
    克隆类型
    • 47
    • 42
    单克隆
    标记
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    This Cadherin-16 antibody is un-conjugated
    应用范围
    • 40
    • 37
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    • 36
    • 25
    • 20
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    • 7
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein A affinity chromatography
    免疫原
    Human protein was used as the immunogen for the recombinant Cadherin 16 antibody.
    克隆位点
    CDH16-1532R
    亚型
    IgG kappa
    Top Product
    Discover our top product CDH16 Primary Antibody
  • 应用备注
    Optimal dilution of the recombinant Cadherin 16 antibody to be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/10e6 cells,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the recombinant Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Cadherin-16 (CDH16)
    别名
    Cadherin 16 (CDH16 产品)
    别名
    cadherin 16 antibody, CDH16 antibody, Cdh16 antibody
    背景
    Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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