Cadherin-16 抗体
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北京 101111
Quick Overview for Cadherin-16 抗体 (ABIN4949253)
抗原
See all Cadherin-16 (CDH16) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Protein A affinity chromatography
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免疫原
- A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Cadherin 16 antibody to be determined by the researcher.\. FACS: 0.5-1 μg/10e6 cells,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Cadherin-16 (CDH16)
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别名
- Cadherin 16
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背景
- Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
抗原
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