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Cadherin-16 抗体

This anti-Cadherin-16 antibody is a 兔 多克隆 antibody detecting Cadherin-16 in IF, FACS 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4949253
发货至: 中国

Quick Overview for Cadherin-16 抗体 (ABIN4949253)

抗原

See all Cadherin-16 (CDH16) 抗体
Cadherin-16 (CDH16)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Cadherin-16 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Cadherin 16 antibody to be determined by the researcher.\. FACS: 0.5-1 μg/10e6 cells,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Cadherin 16 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    Cadherin-16 (CDH16)

    别名

    Cadherin 16

    背景

    Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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