Ferritin 抗体 (Heavy & Light Chain)
Quick Overview for Ferritin 抗体 (Heavy & Light Chain) (ABIN492689)
抗原
See all Ferritin (FE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Heavy & Light Chain
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纯化方法
- Protein A Chromatography Product is 0.2 µm filtered
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免疫原
- Ferritin from Human Spleen
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亚型
- IgG1
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anti-Ferritin (FE) antibody
FE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ferritin (FE) antibodyKD Validated FE 适用: 人, 小鼠, 大鼠 WB, ICC, IF 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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Suitable for use in ELISA. Recommended Pairs for Sandwich ImmunoassayCapture/Detection: ABIN492689 / ABIN263729ABIN492689 / ABIN263732ABIN492689 / ABIN263730ABIN263731 / ABIN492689
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 4.8 mg/mL (OD280nm, E0.1% = 1.4)
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缓冲液
- 10 mM Phosphate, pH 7.4 containing 150 mM Sodium Chloride, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -20 °C for longer.
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- Ferritin (FE)
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别名
- Ferritin
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背景
- Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy, 21 kDa) and L (light, 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit
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途径
- Transition Metal Ion Homeostasis
抗原
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