HAX1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for HAX1 抗体 (N-Term) (ABIN492528)
抗原
See all HAX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
特异性
- This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.
-
产品特性
- Synonyms: HAX-1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-bindingprotein 1
-
纯化方法
- Immunoaffinity Chromotography.
-
免疫原
- A 15 amino acid peptide near the amino terminus of Human Hax1a (GenBank accession no. NP_006109).
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western Blot: Hax1a antibody can be used for detection of Hax1a at 1-2 μg/mL. Positive Control: Human brain tissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
-
别名
- HAX1
-
背景
- The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1
-
基因ID
- 10456
-
UniProt
- O00165
-
途径
- Regulation of Actin Filament Polymerization
抗原
-