GABRD 抗体 (AA 15-34)
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Quick Overview for GABRD 抗体 (AA 15-34) (ABIN492475)
抗原
See all GABRD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 15-34
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特异性
- This antibody detects ~55 kDa Delta GABA-A Receptor protein.
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交叉反应 （详细）
- Species reactivity (tested):Rat and Mouse.
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产品特性
- Synonyms: GABA A receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta
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纯化方法
- Protein G Chromatography.
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免疫原
- Synthetic peptide amino acids 15-34 of rat GABAA Receptor Delta (GABRD).
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亚型
- IgG2a
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anti-GABA A Receptor delta (GABRD) (N-Term) antibody
GABRD 适用: 人, 小鼠, 犬, Cow, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (AA 331-358) antibodyGABRD 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23938 unconjugated
anti-GABA A Receptor delta (GABRD) (N-Term) antibodyGABRD 适用: 人, 大鼠, 小鼠, 犬, Cow, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (N-Term) antibodyGABRD 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, Bat, 豚鼠, Hamster, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (Internal Region) antibodyGABRD 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (AA 331-358) antibodyGABRD 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (AA 19-35), (Extracellular), (N-Term) antibodyKO Validated GABRD 适用: 大鼠 WB, IHC, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (N-Term) antibodyGABRD 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (N-Term) antibodyGABRD 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, Bat, 豚鼠, Hamster, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-GABA A Receptor delta (GABRD) (AA 330-430) antibodyGABRD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1 μg/mL1 μg/mL was sufficient for detection of Delta-1 GABA-A receptor in 10 μg of Rat brain lysateby colorimetric immunoblot analysis using Goat anti-mouse IgG: HRP as the secondaryantibody. Immunoprecipitation: 1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GABRD (GABA A Receptor delta (GABRD))
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别名
- GABRD
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背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (3). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (4).Synonyms: GABA A receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta
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基因ID
- 29689
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UniProt
- P18506
抗原
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