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Lactate Dehydrogenase A 抗体 (N-Term)

The 小鼠 单克隆 anti-Lactate Dehydrogenase A antibody (Clone AT1A4) (ABIN492378) specifically detects Lactate Dehydrogenase A in WB, IF 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN492378
发货至: 中国
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Quick Overview for Lactate Dehydrogenase A 抗体 (N-Term) (ABIN492378)

抗原

See all Lactate Dehydrogenase A (LDHA) 抗体
Lactate Dehydrogenase A (LDHA)

适用

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宿主

  • 105
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小鼠

克隆类型

  • 97
  • 34
单克隆

标记

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This Lactate Dehydrogenase A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

克隆位点

AT1A4
  • 抗原表位

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    AA 1-332, N-Term

    特异性

    The antibody recognizes Human LDHA. Other species not tested.

    产品特性

    Synonyms: LDH-A, L-lactate dehydrogenase A chain, LDH-M, PIG19, NY-REN-59, LDH muscle subunit,Cell proliferation-inducing gene 19 protein, Renal carcinoma antigen NY-REN-59

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    Recombinant human LDHA (1-332aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    ELISA. Western blot (1: 500 - 1: 8000). Immunofluorescence (1: 500 - 1: 8000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Lactate Dehydrogenase A (LDHA)

    别名

    LDHA

    背景

    Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle.Synonyms: Cell proliferation-inducing gene 19 protein, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, NY-REN-59, PIG19, Renal carcinoma antigen NY-REN-59

    基因ID

    3939

    UniProt

    P00338

    途径

    Warburg Effect
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