VAMP8 抗体
Quick Overview for VAMP8 抗体 (ABIN4915080)
抗原
See all VAMP8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This VAMP8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 2~24 amino acids from the N-terminal region of human VAMP8.
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亚型
- IgG1
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anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (AA 1-100) antibody
VAMP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (AA 1-30), (N-Term) antibodyVAMP8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (N-Term) antibodyVAMP8 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1414CT354-12-23-93 unconjugated
anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (AA 1-75) antibodyVAMP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (AA 1-74), (Cytoplasmic Domain) antibodyVAMP8 适用: 人, 大鼠, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (AA 40-89) antibodyVAMP8 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8) (AA 30-79) antibodyVAMP8 适用: 人, 大鼠, 小鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))
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别名
- VAMP8
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背景
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Synonyms: EDB, VAMP-8, Vesicle-associated membrane protein 8, Endobrevin, VAMP8
Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells (By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells (By similarity). Involved in the homotypic fusion of early and late endosomes (By similarity).
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基因ID
- 8673
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UniProt
- Q9BV40
抗原
-
