RAB13 抗体
Quick Overview for RAB13 抗体 (ABIN4913382)
抗原
See all RAB13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein G.
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免疫原
- This RAB13 antibody is generated from a mouse immunized with a recombinant protein between 1-203 amino acids from human RAB13.
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亚型
- IgG1
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anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 66-200) antibody
RAB13 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7G8A4 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 66-200) antibodyRAB13 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E8E2 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 1-203) antibodyRAB13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8H8 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 121-150), (C-Term) antibodyRAB13 适用: 人 WB, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) antibodyRAB13 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 1-203) antibodyRAB13 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 109-137) antibodyRAB13 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19805 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 1-203) antibodyRAB13 适用: 人 WB 宿主: 小鼠 Monoclonal 1600CT845-37-29 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 91-140) antibodyRAB13 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- RAB13 (RAB13, Member RAS Oncogene Family (RAB13))
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别名
- RAB13
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背景
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Synonyms: GIG4, Ras-related protein Rab-13, Cell growth-inhibiting gene 4 protein, RAB13
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin. Thereby, it regulates the assembly and the activity of tight junctions. Moreover, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively. Through its role in tight junction assembly, may play a role in the establishment of Sertoli cell barrier. Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis. Also involved in neurite outgrowth. Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome. Finally, it has been involved in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis.
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基因ID
- 5872
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UniProt
- P51153
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途径
- Cell-Cell Junction Organization
抗原
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