MITF 抗体
Quick Overview for MITF 抗体 (ABIN4911950)
抗原
See all MITF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by Protein G.
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                                            免疫原
- This MITF antibody is generated from a mouse immunized with a recombinant protein of human MITF.
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                                            亚型
- IgG1
 
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                                            应用备注
- WB 1:300-5000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 0.5 μg/μL
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                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            有效期
- 12 months
 
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    - MITF (Microphthalmia-Associated Transcription Factor (MITF))
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                                            别名
- MITF
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                                            背景
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                        Synonyms: MI, WS2, CMM8, WS2A, bHLHe32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, MITF Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. 
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                                            基因ID
- 4286
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                                            UniProt
- O75030
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                                            途径
- Chromatin Binding
 抗原
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