MBD3 抗体
Quick Overview for MBD3 抗体 (ABIN4911809)
抗原
See all MBD3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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    - 
                                            交叉反应
- 人
- 
                                            纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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                                            免疫原
- Purified His-tagged MBD3 protein was used to produced this monoclonal antibody.
- 
                                            亚型
- IgG1
 
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    - 
                                            应用备注
- WB 1:300-5000
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 0.5 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C for 12 months.
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                                            有效期
- 12 months
 
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    - MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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                                            别名
- MBD3
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                                            背景
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                        Synonyms: Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3, MBD3 Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. 
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                                            基因ID
- 53615
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                                            UniProt
- O95983
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                                            途径
- Chromatin Binding
 抗原
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