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MAGED1 抗体

This 小鼠 单克隆 anti-MAGED1 antibody (Clone 5C7) specifically detects MAGED1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN4911723
发货至: 中国
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Quick Overview for MAGED1 抗体 (ABIN4911723)

抗原

See all MAGED1 抗体
MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MAGED1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

5C7
  • 交叉反应

    纯化方法

    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

    别名

    MAGED1

    背景

    Synonyms: NRAGE, DLXIN-1, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, MAGED1, PP2250, PRO2292

    Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

    基因ID

    9500

    UniProt

    Q9Y5V3

    途径

    Neurotrophin Signaling Pathway
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