ITGA6 抗体
Quick Overview for ITGA6 抗体 (ABIN4911222)
抗原
See all ITGA6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- ITA6 recombinant protein is used to produce this monoclonal antibody.
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亚型
- IgG1
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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别名
- ITA6
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背景
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Synonyms: CD49f, VLA-6, ITGA6B, Integrin alpha-6, CD49 antigen-like family member F, ITGA6
Background: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).
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基因ID
- 3655
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UniProt
- P23229
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途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
抗原
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