GNAS 抗体
Quick Overview for GNAS 抗体 (ABIN4910154)
抗原
See all GNAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 小鼠
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纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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免疫原
- This GNAS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from human GNAS.
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亚型
- IgM
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anti-GNAS Complex Locus (GNAS) (AA 42-188) antibody
GNAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A2B7 unconjugated
anti-GNAS Complex Locus (GNAS) (N-Term) antibodyGNAS 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) antibodyKO Validated GNAS 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 42-188) antibodyGNAS 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G6G5 unconjugated
anti-GNAS Complex Locus (GNAS) (N-Term) antibodyGNAS 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 310-404) antibodyGNAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (Internal Region) antibodyVerified GNAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 1-394) antibodyGNAS 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-GNAS Complex Locus (GNAS) (AA 287-315), (C-Term) antibodyGNAS 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33001 unconjugated
anti-GNAS Complex Locus (GNAS) (AA 286-315), (C-Term) antibodyGNAS 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- GNAS (GNAS Complex Locus (GNAS))
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别名
- GNAS
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背景
- Optional[synonyms]: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
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UniProt
- Q5FWY2
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途径
- Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
抗原
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