TOR1A 抗体
Quick Overview for TOR1A 抗体 (ABIN4908959)
抗原
See all TOR1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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免疫原
- Purified His-tagged DYT1 protein(Fragment) was used to produced this monoclonal antibody.
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亚型
- IgG1
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anti-Torsin Family 1, Member A (Torsin A) (TOR1A) (AA 33-321) antibody
TOR1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Torsin Family 1, Member A (Torsin A) (TOR1A) (AA 41-333) antibodyTOR1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Torsin Family 1, Member A (Torsin A) (TOR1A) (AA 88-125) antibodyTOR1A 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Torsin Family 1, Member A (Torsin A) (TOR1A) (AA 201-250) antibodyTOR1A 适用: 人, 小鼠, 犬, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Torsin Family 1, Member A (Torsin A) (TOR1A) (AA 63-332) antibodyTOR1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Torsin Family 1, Member A (Torsin A) (TOR1A) antibodyTOR1A 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- TOR1A (Torsin Family 1, Member A (Torsin A) (TOR1A))
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别名
- DYT1
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背景
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Synonyms: DQ2, DYT1, Torsin-1A, Dystonia 1 protein, Torsin ATPase-1A, Torsin family 1 member A, TOR1A, TA, TORA
Background: Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.
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基因ID
- 1861
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UniProt
- O14656
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途径
- SARS-CoV-2 Protein Interactome
抗原
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