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CXCR4 抗体 (AA 151-300)

CXCR4 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4908443
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    抗原表位
    • 16
    • 15
    • 15
    • 12
    • 7
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 151-300
    适用
    • 137
    • 79
    • 62
    • 21
    • 10
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 117
    • 22
    • 9
    • 5
    • 1
    克隆类型
    • 125
    • 29
    多克隆
    标记
    • 92
    • 7
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    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
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    • 1
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 107
    • 48
    • 46
    • 34
    • 26
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    • 25
    • 25
    • 18
    • 10
    • 9
    • 6
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    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    交叉反应
    小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse CXCR4
    亚型
    IgG
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CXCR4 (CXCR4 产品)
    背景

    Synonyms: CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor, Pre-B-cell-derived chemokine receptor, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Cxcr4

    Background: Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

    基因ID
    12767
    UniProt
    P70658
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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