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CDK5 抗体

The 小鼠 单克隆 anti-CDK5 antibody (Clone 1C9) (ABIN4907877) specifically detects CDK5 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN4907877
发货至: 中国
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Quick Overview for CDK5 抗体 (ABIN4907877)

抗原

See all CDK5 抗体
CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CDK5 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

1C9
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein G.

    免疫原

    This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 160-286 amino acids from human.

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

    别名

    CDK5

    背景

    Synonyms: LIS7, PSSALRE, Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit, CDK5, CDKN5

    Background: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

    基因ID

    1020

    UniProt

    Q00535

    途径

    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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