CCL5 抗体 (AA 71-89) (PE)
Quick Overview for CCL5 抗体 (AA 71-89) (PE) (ABIN4907592)
抗原
See all CCL5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-89
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CCL5
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibody
CCL5 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 62-91) antibodyCCL5 适用: 人, 小鼠, 豚鼠, Pig ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) antibodyCCL5 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) antibodyCCL5 适用: 人 WB, ELISA, Func, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) antibody (Biotin)CCL5 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 猕猴 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- FCM(1:20-100)
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存条件
- -20 °C
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储存方法
- Store at 4°C
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有效期
- 12 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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别名
- CCL5/ RANTES
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背景
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Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils (PubMed:1679162, PubMed:13864, PubMed:8525373, PubMed:9516414, PubMed:15923218). May also be an agonist of the G protein-coupled receptor GPR75, stimulating inositol trisphosphate production and calcium mobilization through its activation. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells (PubMed:23979485).
Subcellular location: Secreted, Helical
Synonyms: SISd, eoCP, SCYA5, RANTES, TCP228, D17S136E, SIS-delta, C-C motif chemokine 5, Eosinophil chemotactic cytokine, Small-inducible cytokine A5, T cell-specific protein P228, T-cell-specific protein RANTES, CCL5 -
基因ID
- 6352
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UniProt
- P13501
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
抗原
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