RCAN3 抗体 (AA 151-241) (AbBy Fluor® 594)
Quick Overview for RCAN3 抗体 (AA 151-241) (AbBy Fluor® 594) (ABIN2811039)
抗原
See all RCAN3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-241
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Calcipressin 3
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亚型
- IgG
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anti-RCAN Family Member 3 (RCAN3) (C-Term) antibody
RCAN3 适用: 人, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RCAN Family Member 3 (RCAN3) (Middle Region) antibodyRCAN3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-RCAN Family Member 3 (RCAN3) (AA 194-222), (C-Term) antibodyRCAN3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RCAN3 (RCAN Family Member 3 (RCAN3))
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别名
- Calcipressin 3
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背景
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Synonyms: Calcipressin-3, Down syndrome candidate region 1 like 2, regulator of calcineurin 3, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, DSCR1L2, hRCN3, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3.
Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.
抗原
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