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BANP 抗体

The 小鼠 单克隆 anti-BANP antibody is suitable to detect BANP in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN4906466
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BANP 抗体 (ABIN4906466)

抗原

See all BANP 抗体
BANP (Protein BANP (BANP))

适用

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宿主

  • 10
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小鼠

克隆类型

  • 12
  • 1
单克隆

标记

  • 13
This BANP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4C2
  • 交叉反应

    纯化方法

    Purified by Protein G.

    免疫原

    This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    BANP (Protein BANP (BANP))

    别名

    BANP

    背景

    Synonyms: BEND1, SMAR1, SMARBP1, Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP

    Background: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

    基因ID

    54971

    UniProt

    Q8N9N5
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